Background Informed consent confers upon participants the right to decline or accept participation in a study in equal measure. Consent declines can be used as a potential metric to assess the adequacy of the informed consent process. Limited literature is available on the reporting of consent declines in Clinical Research. We evaluated randomized controlled trials published in three high-impact factor journals for consent declines (four-year period) to assess the extent of exertion of autonomy by research participants. Methods CONSORT flow charts (...) in RCTs published in New England Journal of Medicine (NEJM), The Lancet and Journal of the American Medical Association (JAMA) between 2012 and 2015 were evaluated. The total and per journal proportion of RCTs reporting consent declines was calculated. Percentage of consent declines was also compared based on number of centers (single centric vs. multicentric) and type of setting (developed vs. developing). Between-groups analysis was done using Chi Square, Chi Square for trend and a Crude odds ratio [95% C.I] (cOR) were calculated. Results Only 3.7% (1103/29,825) of the published articles were RCTs. Of the 1103 RCTs, only 532 (48.2%) reported consent declines. JAMA had the highest RCTs reporting consent declines (171/267.64%), the Lancet [129,150/781,924, 16.5%] had the most participants declining consent. Difference was significant using Chi square for linear trend [ p < 0.00001]. Consent decline rate was higher in developed countries relative to developing countries [cOR(95% C.I): 2.27(2.23,2.32), p < 0.000001] and in single centric versus multicentric studies [cOR (95% C.I): 3.63(3.56,3.71), p < 0.0000001]. Conclusion Both authors and journal editors need to ensure better reporting of consent declines. (shrink)

The paper presents and applies Hilbert's Epsilon Calculus, first describing its standard proof theory, and giving it an intensional semantics. These are contrasted with the proof theory of Fregean Predicate Logic, and the traditional (extensional) choice function semantics for the calculus. The semantics provided show that epsilon terms are referring terms in Donnellan's sense, enabling the symbolisation and validation of argument forms involving E-type pronouns, both in extensional and intensional contexts. By providing for transparency in intensional constructions they support a (...) Model Conceptualism to contrast with traditional intensional logic's Modal Realism. But epsilon-terms also symbolise fictions, and through their difference from iota terms enable the solution of a number of outstanding puzzles about Direct Reference and de re beliefs. (shrink)

The author has made this treatise on Madhva’s realistic school of Ved?nta philosophy convincing to the modern mind by employing western logical apparatus in substantiating Madhva’s ideas. Following the Indian classical tradition, the author has examined the validity of Advaitaved?nta, the Absolute Monism of ?a?kara and Bh?skara as P?rvapak?a, and logically proved its inconsistencies. He has then established the Dvaitasiddh?nta i.e., the Monotheistic Dualism of Madhva. He has successfully brought out the nuances of the realistic school of Indian philosophical thought (...) in this work. A Modern Introduction to M?dhva Philosophy is Prof B H Kotabagi’s posthumous publication. (shrink)

Brian Wormald provides a fundamental reappraisal of one of the most complex and innovative figures of the late-Elizabethan and Jacobean age. In the centuries since his death, Francis Bacon (1561-1626) has been perceived and studied as a promoter and prophet of the philosophy of science--natural science--but he saw himself also as a clarifier and promoter of what he called "policy" or the study and improvement of the structure and function of civil states. Mr. Wormald shows that Bacon was concerned equally (...) with the knowledge of the world of nature and with that of policy. The junction between the two enterprises was effected by his work in history; and in the end it was Bacon's conception and practice of history that provided the answer to his efforts to advance policy and natural philosophy. (shrink)

Recovers some of the value in the Wittgensteinian period of philosophy, using certain logical systems: Prior's theory of operators and Hilbert's epsilon calculus. This work applies, discursively, the previous largely technical results published in Prolegomena to Formal Logic (Aldershot, Gower 1989) and Intensional Logic (Aldershot, Ashgate 1994) to resolve matters of current interest in philosophy, logic and linguistics - notably attacking a variety of realisms found in comtemporary cognitive science and the philosophy of mathematics.

One of the claims made for C. S. Peirce's existential graphs has been that they are a deductively complete formulation of first-order logic with identity. As Peirce presented them, this is true only for certain versions of first-order logic :those which do not include terms for individuals. I amend Peirce's rules here, showing, in particular, how they are capable of demonstrating that, for instance, ?Jack is in the kitchen? contradicts ?Jack is not in the kitchen?

In a previous issue of Philosophical Investigations Professor Radford provides a counterexample to the equation1: a word is on the tip of a man's tongue IFF (a) he can recognize the word and (b1) he believes he may be able to produce It (fairly soon).

In list-method directed forgetting, reexposure to forgotten List 1 items has been shown to reduce directed forgetting. proposed that reexposure to a few List 1 items only during a direct test of memory reinstates the entire List 1 episode. In the present experiments, part-list reexposure in the context of indirect as well as direct memory tests reduced directed forgetting. Directed forgetting was reduced when 50% or more of the items were reexposed, and was intact when only 25% were reexposed. Furthermore, (...) part-list reexposure appeared to reinstate only reexposed items-not the entire List 1 episode. (shrink)